Quincke’s Disease: Isolated Uvulitis

Author Affiliation
Joseph R. Shiber, MD University of Florida, Jacksonville, Florida
Emily Fontane, MD University of Florida, Jacksonville, Florida

A 27 year-old previously healthy man complained of sudden onset of gagging and foreign-body sensation that awoke him. He reported one day of nasal and sinus congestion. He had become concerned when he saw his extremely enlarged uvula while looking in a mirror (Figure). He had no fever, throat pain, or difficulty breathing, swallowing, or speaking. Prior to going to bed, he had taken an over-the-counter cold and allergy medication which he had taken previously without any adverse effects; he was not taking any other medications. He was admitted to the intensive care unit overnight for close observation and treated with nebulized racemic epinephrine, intravenous antihistamines and steroids. Empiric antibiotics directed against the most common infectious agents, Haemophilus and Streptococcus species were given.1 He had rapid improvement in his symptoms over the next 24 hours and was discharged home. Uvulitis can be caused by mechanical trauma, chemical or thermal injury, infection, or angioedema of immunologic or non-immunologic origin.2

Figure Enlarged uvula.


Enlarged uvula.


Full text available through open access at http://escholarship.org/uc/uciem_westjem

Address for Correspondence: Joseph Shiber, MD, University of Florida, 655 W. 8th St. Jacksonville, FL 32209. Email: shiberj@bellsouth.net. 9 / 2014; 15:663 – 663

Submission history: Revision received May 5, 2014; Accepted June 9, 2014

Conflicts of Interest: By the WestJEM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. The authors disclosed none.


1 Lathadevi HT, Karadi RN, Thobbi RV Isolated uvulitis: an uncommon but not rare clinical entity. Indian J. OHNS. 2005; 57:139-140

2 Cohen M, Chhetri DK, Head C Isolated uvulitis. ENT J. 2007; 86:462-464