|Patrick Burns, MD||University of Washington, Department of Emergency Medicine, Seattle, Washington|
|Shelley Yang, MD||University of Washington, Department of Dermatology, Seattle, Washington|
|Jared Strote, MD, MS||University of Washington, Department of Emergency Medicine, Seattle, Washington|
A 48-year-old male presented with body aches and a chronic rash. He had no medical history aside from two unsuccessful treatments for presumed scabies and a recent diagnosis of psoriasis. Physical exam revealed hypotension, tachycardia, and profound, diffuse yellow crusting of the skin with erythematous erosions covering non-crusted areas (Figure). The patient was resuscitated and treated for septic shock while microscopic evaluation of scrapings of the crusted skin was performed (Video).
The patient had crusted (Norwegian) scabies with associated Enterobacter sepsis.
Crusted scabies is a rare skin infestation caused by Scarcoptes scabiei with parasitic loads in the thousands to millions.
In contrast to common scabies infections, it tends to affect immunosuppressed or debilitated patients and pruritus is not prominent. Patients present with scaly, hyperkeratotic, gray to erythematous plaques. Given its similarity to other dermatologic processes, misdiagnosis is common. Clinical diagnosis is aided by microscopic identification of scabies mites, eggs or feces in skin scrapings or under fingernails. Occasionally videodermatoscopy or biopsy is necessary. Skin breakdown can lead to cellulitis and systemic bacterial infection.1-2
Treatment for mild cases is the same as for uncomplicated scabies infections. For severe cases, oral or intravenous (IV) ivermectin should be given. 1
After resuscitation, the patient was admitted with broad-spectrum IV antibiotics and ivermectin as well as topical permethrin. A Human Immunodeficiency Virus test sent from the emergency department came back positive. After a prolonged hospital course with multiple complications from his skin breakdown and sepsis, he was discharged with full eradication of his scabies infestation.
Section Editor: Sean O. Henderson, MD
Full text available through open access at http://escholarship.org/uc/uciem_westjem
Address for Correspondence: Jared Strote, MD, MS, University of Washington Medical Center, Division of Emergency Medicine, Box 356123, Seattle, WA 98195. Email: firstname.lastname@example.org. 7 / 2015; 16:587 – 587
Submission history: Revision received May 6, 2015; Accepted May 19, 2015
Conflicts of Interest: By the WestJEM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. The authors disclosed none.
1. Guldbakke KK, Khachemoune A. Crusted scabies: a clinical review. J Drugs Dermatol. 2006;5(3):221-227.
2. Hulbert TV, Larsen RA. Hyperkeratotic (Norwegian) scabies with gram-negative bacteremia as the initial presentation of AIDS. Clin Infect Dis. 1992;14(5):1164-1165.