We were excited to read the article by Michael Wilson et al1 in the March 2012 issue of theWestern Journal of Emergency Medicine regarding pharmacologic strategies for the management of agitated patients in the emergency setting. This article highlights several important points including the optimal management of stimulant-induced agitation and the feasibility of and reasons for differentiating acute alcohol intoxication from withdrawal, as optimal pharmacologic interventions for each might vary.
In this article, the authors review the use of a variety of first-generation antipsychotic drugs, second-generation antipsychotic drugs, and benzodiazepines for treatment of acute agitation, and propose specific guidelines for treatment of agitation associated with a variety of conditions, including acute intoxication, psychiatric illness, delirium, and multiple or idiopathic causes.
