De Winter T-wave Pattern in Proximal Left Anterior Descending Artery Occlusion

Author Affiliation
David Gregory, MD Wellspan York Hospital, Department of Emergency Medicine, York, Pennsylvania
Bryan Wexler, MD Wellspan York Hospital, Department of Emergency Medicine, York, Pennsylvania
Brent Becker, MD Wellspan York Hospital, Department of Emergency Medicine, York, Pennsylvania

Case presentation
Discussion

ABSTRACT

Case Presentation

We describe a case of an acute myocardial infarction with an atypical electrocardiogram showing a de Winter T-wave pattern suggesting the 100% proximal left anterior descending artery occlusion seen on emergent cardiac catheterization.

Discussion

Timely recognition of acute myocardial ischemia is paramount for emergency providers. As highlighted in this case, It is important to be mindful of atypical electrocardiogram findings, such as de Winter T-waves, which suggest acute myocardial ischemia.

CASE PRESENTATION

A 56-year old male with a history of hypertension presented to the emergency department with one hour of crushing chest pain radiating to the left arm and neck. The symptoms began following exertion, but failed to alleviate with rest. Initial electrocardiogram (ECG) demonstrated hyperacute T-waves with associated ST-segment depression in the precordial leads, consistent with a de Winter T-wave pattern1 (Image 1). Due to concern for acute myocardial infarction (AMI), cardiology was consulted for possible percutaneous intervention (PCI).

 

Image 1
Tall, prominent, symmetric T-waves with associated ST-segment depression in precordial leads (arrows).

Emergent cardiac catheterization was performed and revealed a 100% occlusion of the proximal left anterior descending artery (Image 2). After successful PCI, the patient experienced no further complications and was subsequently discharged on appropriate medical management.

 

Image 2
Coronary angiography demonstrating occlusion of the proximal left anterior descending artery (arrow).

DISCUSSION

De Winter T-waves are characteristic prominent, symmetric precordial T-waves with associated upsloping ST-segment depression at the J-point.1 This ECG pattern lacks traditional ST-segment elevations but is indicative of acute anterior ischemia.2 Prior studies suggest approximately 2% of left anterior descending artery occlusions present with de Winter T-waves.3

Diagnosis of AMI can be challenging. Emergency physicians are well trained to recognize the pattern of contiguous ST-segment elevations with reciprocal depressions that define traditional criteria for an ST-elevated myocardial infarction (STEMI)2; however, clinicians must also be cognizant of atypical ECG findings that suggest acute myocardial ischemia, such as Wellens syndrome, patterns that meet modified Sgarbossa criteria, and as in this case, de Winter T-waves. These less common ECG nuances must be recognized and approached as a STEMI equivalent.

 

CPC-EM Capsule

What do we already know about this clinical entity?

De Winter T-waves are hyperacute precordial T-waves with associated upsloping ST-segment depressions that indicate acute anterior myocardial infarction (MI).

What is the major impact of the image(s)?

The electrocardiogram (ECG) demonstrates the de Winter T-wave pattern that emergency physicians must recognize as a ST-segment elevated MI equivalent.

How might this improve emergency medicine practice?

Recognition of atypical ECG patterns consistent with acute MI can facilitate prompt coronary intervention and salvage at-risk myocardium.

 

Footnotes

Section Editor: Christopher Sampson, MD

Full text available through open access at http://escholarship.org/uc/uciem_cpcem

The authors attest that their institution requires neither Institutional Review Board approval, nor patient consent for publication of this image in emergency medicine. Documentation on file.

Address for Correspondence: David Gregory, MD, Wellspan York Hospital, Department of Emergency Medicine, 1001 S. George Street, York, PA 17403. Email: dave.l.gregory@gmail.com. 4:476 – 477

Submission history: Revision received March 18, 2020; Submitted May 14, 2020; Accepted May 20, 2020

Conflicts of Interest: By the CPC-EM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. The authors disclosed none.

REFERENCES

1. de Winter RJ, Verouden NJ, Wellens HJ, et al. A new ECG sign of proximal LAD occlusion. NEJM. 2008;359:2071-3.

2. Thygesen K, Alpert J, Jaffe A, et al. Fourth universal definition of myocardial infarction (2018). Circulation. 2018;138:e618-51.

3. Verouden NJ, Koch KT, Peters RJ, et al. Persistent precordial “hyperacute” T-waves signify proximal left anterior descending artery occlusion. Heart. 2009;95(20):1701-6.